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News Release on Viral Infections Research: September-2018

September 3, 2018 by Editor NetKumar

An unconventional immune cell capable of fighting viral infections

Research light-emitting diode by the University of Birmingham has known a completely unique unconventional form of immune cell capable of fighting infective agent infections.

The study revealed nowadays in Nature Communications and applied unitedly with the tutorial eye, European country, and Skolkovo Institute of Science and Technology, Russia, focussed on T cells that management our system. [1]

Giving the Genes a Shuffle: Using Natural Variation to Understand Host Genetic Contributions to Viral Infections

The laboratory mouse has well-tried a useful model to spot host factors that regulate the progression and outcome of virus-induced sickness. The paradigm is to use single-gene knockouts in inbred mouse strains or genetic mapping studies victimization biparental mouse populations. However, genetic variation among these mouse strains is prescribed compared with the variety seen in human populations. to deal with this disconnect, a multiparental mouse population has been developed to specifically dissect the multigenetic regulation of complicated sickness traits. [2]

RNA interference as a prospective tool for the control of human viral infections

RNA interference (RNAi), that is mediated by tiny officious RNAs (siRNAs) derived from microorganism order or its replicative intermediates, may be a natural antiviral defense in plants, fungi, and invertebrates. whether or not RNAi naturally protects humans from microorganism invasion remains a matter of dialogue. even so, exogenous siRNAs area unit able to halt virus infection in mammals. [3]

Cerebral toxoplasmosis in a cat with feline leukemia and feline infectious peritonitis viral infections.

A regular young cat died when neurologic involvement. organic chemistry pointed to feline infectious rubor (FIP). the ultimate diagnosing was severe multifocal cephalitis because of Toxoplasma gondii. The presence of the parasite within the brain was confirmed by victimization immunohistochemical staining. [4]

An occurrence of Hepatitis B and C Viral Infections among Pregnant Women in Calabar, Cross River State, Nigeria

Aims: to see the prevalence of HBV and HCV among pregnant girls in Calabar, and therefore the doable predisposing factors of the unwellness.

Study Design: This was a cross-sectional study.

Place and period of Study: This study was applied in Calabar, the capital town of Cross watercourse State, the Federal Republic of Nigeria between might, 2014 and Gregorian calendar month, 2015.

Methodology: moral approval was obtained, consent forms were signed by the patients, questionnaires were additionally administered to capture socio-demographic data followed by assortment and process of specimens. 5 milliliter (5 ml) of blood was collected from three hundred pregnant (test) and a hundred non-pregnant (control) subjects and their sera tested for HBV and HCV victimization One step HBsAg strip and One step Anti-HCV strip. each factory-made by ACON Laboratories incorporated, USA. Questionnaires were additionally administered. [5]

Reference

[1] Unconventional immune cell capable of fighting viral infections

Date: May 2, 2018, Source: University of Birmingham (web link)

[2] Giving the Genes a Shuffle: Using Natural Variation to Understand Host Genetic Contributions to Viral Infections

Leist SR, Baric RS. Giving the Genes a Shuffle: Using Natural Variation to Understand Host Genetic Contributions to Viral Infections. Trends in Genetics. 2018 Aug 18. (web link)

[3] RNA interference as a prospective tool for the control of human viral infections

Poranen MM. RNA interference as a prospective tool for the control of human viral infections. Frontiers in Microbiology. 2018;9:2151. (web link)

[4] Cerebral toxoplasmosis in a cat with feline leukemia and feline infectious peritonitis viral infections.

Zandonà L, Brunetta R, Zanardello C, Vascellari M, Persico L, Mazzolini E. Cerebral toxoplasmosis in a cat with feline leukemia and feline infectious peritonitis viral infections. The Canadian veterinary journal= La revue veterinary Canadienne. 2018 Aug;59(8):860-2. (web link)

[5] Occurrence of Hepatitis B and C Viral Infections among Pregnant Women in Calabar, Cross River State, Nigeria

  1. C. Inyang-Etoh1*, R. U. Aganyi1, T. U. Agan2 and U. Opara-Osuoha3

1Department of Medical Laboratory Science, Faculty of Allied Medical Sciences, College of Medical Sciences, University of Calabar, Calabar, Nigeria.

2Department of Obstetrics and Gynaecology, Faculty of Medicine and Dentistry, College of Medical Sciences, University of Calabar, Calabar, Nigeria.

3Department of Biology, College of Science and Technology, Temple University, 1900 North 12th St, Philadelphia, PA 19122, USA. (web link)

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