The objective of whole follow integrate, writing and Pharmacological doom of 2-Amino-N-(substituted alkyl) benzoxazole-5- carboxamides for opposing-irritating and antioxidant exercises counterbalance from 4-carbomethoxynitrophenol. Evaluation of the compounds told Vc(R=ethyl), Ve(R=propyl) and Vg (R=diisopropyl) V g (R=propyl) as final direct individual. When outstanding to the standard ascorbic acid, compound Vf (R=isopropyl) presented a densely grown quota of free radical scavenging project accompanying an IC 50 of 4.65. Vf is deduced as a drug that has two together opposing-annoying and antioxidant ownerships.

Author(s) Details:

Arunadevi Parlapalli,
Department of Pharmaceutical Chemistry, University College of Pharmaceutical Sciences, Kakatiya University, Warangal 506009, India.

Kishore,
Department of Pharmaceutical Chemistry, University College of Pharmaceutical Sciences, Kakatiya University, Warangal 506009, India

Manasa Cidda,
Department of Pharmaceutical Chemistry, University College of Pharmaceutical Sciences, Kakatiya University, Warangal 506009, India.

Sarangapani Manda,
Department of Pharmaceutical Chemistry, University College of Pharmaceutical Sciences, Kakatiya University, Warangal 506009, India.

Please see the link here: https://stm.bookpi.org/COPS-V2/article/view/9171

Keywords: Benzoxazole, synthesis, anti-inflammatory, antioxidant

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