The study aimed to investigate the adsorptive interactions of metal hexacyanoferrates (II) and ethanol and acetone extracts of natural antifungals. Nickel, manganese and copper hexacyanoferrates (II) were synthesized and characterized by elemental and spectral studies. Each metal hexacyanoferrate (II) was combined with two natural antifungals: coconut (Cocos nucifera) and ochro (Abelmoschusesculentus) leaf extract. The antifungal potential was executed by the disc diffusion method. The acetone and ethanol extract of A. esculentus at 10 mg/m L paired with copper and nickel ferrocyanides, respectively were found to possess the most effective antifungal potential. Each interaction pair was further analyzed through infrared spectral studies and phytochemical analysis. The interaction of natural antifungals Azadirachta indica (neem), Ocimum sanctum (tulsi), Cassia obtusifolia (money bush), Cassia alata (canicro bush) and Targetes patula (marigold) with manganese, silver and titanium ferrocyanides and their medical applications were also evaluated.
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