The current study wanted to determine the anthelmintic project of Lindernia madayiparense against Indian earthworms, Pheretima posthuma. Helminthiasis poses a serious risk to the public’s well-being and increases the incidence of pneumonia, eosinophilia, emptiness, and malnutrition in underdeveloped countries. Decoction and continuous hot distillation methods were used to constitute various extracts. To recognize the presence of phytochemical constituents, preliminary approximate analysis was acted on all L. madayiparanse extracts. The best anthelmintic activity between the studied extracts against earthworms was demonstrated for one ethanol extract, that was also further other extracts at all concentrations and carefully matched the common medication, albendazole. A shot-dependent paralytic effect and organize of death were present fully of the studied extracts. Certain results led to the theory that the existence of these subordinate metabolites, such as alkaloids, flavonoids, terpenoids, tannins, and saponins, grant permission be the cause of the observed anthelmintic activity.

Author(s) Details:

S. Umakrithika,
GITAM School of Pharmacy, Gandhi Institute of Technology and Management (Deemed to be) University, Hyderabad, Telangana-500046, India.

Kannan Kamarajan,
Department of Pharmacy, Faculty of Engineering and Technology, Annamalai University, Annamalainagar-608002, Tamil Nadu, India.

Prabal Kumar Manna,
Department of Pharmacy, Faculty of Engineering and Technology, Annamalai University, Annamalainagar-608002, Tamil Nadu, India.

Please see the link here: https://stm.bookpi.org/COPS-V2/article/view/9168

Keywords: Lindernia madayiparense, anthelmintic, Pheretima posthuma, dose-dependent, ethanol extract

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