Skip to content
Menu
Science News Online
  • HOME
  • HEALTH
  • ENVIRONMENT
  • SPACE
  • HUMANS
  • PHYSICS
  • CHEMISTRY
Science News Online

News Update on Oral Cancer Research: Sep – 2019

September 6, 2019 by Editor NetKumar

Oral Cancer and Precancerous Lesions

In the us, cancers of the oral fissure and cavum represent close to 3 p.c of all malignancies in men and 2 p.c of all malignancies in girls. The yankee Cancer Society estimates that twenty eight,900 new cases of carcinoma are going to be diagnosed in 2002, and nearly seven,400 individuals can die from this unwellness. Over ninety p.c of those tumors square measure epithelial cell carcinomas, that arise from the oral tissue layer lining. In spite of the prepared accessibility of the oral fissure to interrogation, these malignancies still square measure typically not detected till a late stage, and also the survival rate for carcinoma has remained basically unchanged over the past 3 decades. [1]

Epidemiology and prevention of oral cancer

Descriptive medical specialty of oral and tubular cavity cancer over the last four decades is reviewed, with specific specialize in Europe. Substantial rises in mortality rates are ascertained for younger males, principally in japanese Europe. The freelance role of alcohol and tobacco and their interaction on oral carcinogenesis is mentioned, since these factors account for concerning 3 quarters of oral cancers in Europe. The influence of dietary factors, and specially of a diet poor in recent fruit and vegetables on oral carcinogenesis, is additionally mentioned, since diet could account for 10–15% of carcinoma cases in Europe. Finally, among different carcinogens, the chance of human papillomavirus involvement within the aetiology of cancer of the oral fissure and throat is overviewed. Implications for interference are mentioned. [2]

Human Papillomavirus and Oral Cancer: The International Agency for Research on Cancer Multicenter Study

Background: Human papillomavirus (HPV), the cause of cervical cancer, seems to be concerned within the etiology of cancer of the mouth and cavum. to research these associations, we tend to conducted a multicenter case-control study of cancer of the mouth and cavum in 9 countries. Methods: we tend to recruited 1670 case patients (1415 with cancer of the mouth associate degreed 255 with cancer of the oropharynx) and 1732 management subjects and obtained an interview, oral exfoliated cells, and blood from all participants and recent diagnostic assay specimens from case patients. HPV desoxyribonucleic acid was detected by enzyme chain reaction (PCR). Antibodies against HPV16 L1, E6, and E7 proteins in plasma were detected with enzyme-linked immunosorbent assays. Multivariable models were used for case-control and case-case comparisons. [3]

Assessing confidence in the understanding and management of oral cancer among medical and dental undergraduates at a UK university

Introduction carcinoma is that the eighth most typical cancer within the world and related to a high rate of morbidity and mortality. applicable and early diagnosing of the condition is related to improved patient outcomes, associate degreed an improvement in five-year survival rates.

Aims we tend to aim to establish if dental and medical students have similar amounts of confidence within the understanding and management of carcinoma at intervals an outsized United Kingdom of Great Britain and Northern Ireland university. [4]

Alterations in Oral Cancer Gene Expression in Response to Melatonin

Aims: endocrine (MLT) exerts oncostatic effects on varied neoplasm sorts presumptively by inhibiting cell proliferation and promoting necrobiosis. the first aim of this study was to analyze melatonin-induced changes in organic phenomenon patterns in 2 completely different oral squamous malignant neoplastic disease cell lines (OSCC).

Methodology: This was a prospective non-randomized experimental study style that was conducted at Department of medical specialty Sciences at the University of Battle Born State, urban center – faculty of medical specialty between might 2016 and March 2017. The SCC25 and CAL27 cell lines were civilised with and while not MLT (10 ug/mL) for seventy two hours, and total cellular ribonucleic acid was isolated and reborn to complementary DNA. The expression of ninety two genes related to the molecular mechanisms of cancer and 4 endogenous management genes were examined by qRT-PCR. The fold amendment with regard to management levels were calculated victimisation the comparative technique or delta-delta ddCt formula. [5]

Reference

[1] Neville, B.W. and Day, T.A., 2002. Oral cancer and precancerous lesions. CA: a cancer journal for clinicians, 52(4), pp.195-215. (Web Link)

[2] La Vecchia, C., Tavani, A., Franceschi, S., Levi, F., Corrao, G. and Negri, E., 1997. Epidemiology and prevention of oral cancer. Oral oncology, 33(5), pp.302-312. (Web Link)

[3] Herrero, R., Castellsagué, X., Pawlita, M., Lissowska, J., Kee, F., Balaram, P., Rajkumar, T., Sridhar, H., Rose, B., Pintos, J. and Fernández, L., 2003. Human papillomavirus and oral cancer: the International Agency for Research on Cancer multicenter study. Journal of the National Cancer Institute, 95(23), pp.1772-1783. (Web Link)

[4] Assessing confidence in the understanding and management of oral cancer among medical and dental undergraduates at a UK university
Ross M. Keat, Meeral Makwana, Harriet E. Powell, Ana Poveda & Rui Albuquerque
British Dental Journalvolume 227, pages153–157 (2019) (Web Link)

[5] Hartounian, A., Alessandro Retis, G., Kingsley, K. and Howard, K. (2018) “Alterations in Oral Cancer Gene Expression in Response to Melatonin”, Journal of Complementary and Alternative Medical Research, 6(2), pp. 1-8. doi: 10.9734/JOCAMR/2018/44008. (Web Link) (Web Link)

Leave a Reply Cancel reply

Your email address will not be published. Required fields are marked *

Search

Categories

  • Abstract (9)
  • Agricultural and Food Science (90)
  • Agricultural Extension (6)
  • Agricultural Science (236)
  • Agriculture (216)
  • ANIMALS (7)
  • Arts & Education (16)
  • Arts & Education and Social Studies (7)
  • Arts & Social Sciences (19)
  • Biochemistry (35)
  • Biological Science (224)
  • BIOLOGY (164)
  • Biotechnology (38)
  • Blood (17)
  • Business (26)
  • Cancer and Tumor (17)
  • Cardiology (7)
  • Chemical and Material Science (79)
  • chemical science (237)
  • CHEMISTRY (77)
  • Chemistry and Biochemistry (213)
  • Climate Change (1)
  • Computr Science (6)
  • corporate (1)
  • Dentistry (2)
  • Dermatology (1)
  • Disease and Health (131)
  • EARTH (8)
  • Earth Science (55)
  • Economics (92)
  • Economics and Management (314)
  • Education (130)
  • Education and Social Studies (46)
  • Endocrinology (1)
  • ENERGY (8)
  • Energy Research (3)
  • engineering (730)
  • Engineering Research (67)
  • ENVIRONMENT (49)
  • Environment & Ecology (15)
  • Environment and Earth (9)
  • Environment and Earth Science (194)
  • Food Science (2)
  • Gastroenterology (1)
  • Geography (16)
  • Geography, Environment and Earth Sciences (32)
  • Geological Science (8)
  • Gynaecology and Obstetrics (2)
  • HEALTH (109)
  • Health & Food (3)
  • Health Research (97)
  • Hematology (4)
  • Humanities and Social Sciences (66)
  • HUMANS (17)
  • Immunology (1)
  • Journal (6)
  • Language, Literature and Education (116)
  • Literature (1)
  • Literature and Education (8)
  • Materials Science (1)
  • Mathamatical Science (2)
  • Mathematical & Human Engineering Sciences (1)
  • Mathematical Research and Computer Science (31)
  • Mathematics and Computer Science (435)
  • Medical Science (181)
  • Medicinal Plants (14)
  • medicine (49)
  • medicine and medical (1,307)
  • Medicine and Medical Research (345)
  • Medicine and Medical Science (177)
  • Medicine and Pharmacy (38)
  • Microbiology (16)
  • Microbiology and Biotechnology (143)
  • Multidisciplinary (1)
  • NATURE (4)
  • Nephrology (2)
  • Neurology (1)
  • NEWS (106)
  • Nutrition & Food (12)
  • Ophthalmology (5)
  • Pharmaceutical (251)
  • Pharmaceutical (1)
  • Physical Science (318)
  • PHYSICS (113)
  • Physics and Astronomy (20)
  • Plant and Soil Research (37)
  • Plant Biology (1)
  • Psychology (1)
  • romance & drama (1)
  • Science and Technology (695)
  • Social Science (25)
  • Social Sciences and Humanities (120)
  • Social Studies (14)
  • Soil Science (15)
  • SPACE (29)
  • Sustainable Development (1)
  • TECH (30)
  • Uncategorized (20)
  • Zoology (9)

Comments

    ©2022 Science News Online | Powered by WordPress and Superb Themes!