At doses of 50 and 100 mg/kg, the analgesic efficacy of fractions and aqueous residual of pericarpium methanolic extract of Balanites roxburghi will be evaluated. The fruit of the allied species Balanites aegyptiaca is used as an analgesic in Ayurvedic medicine. Pain is a common occurrence in all species, at least in vertebral animals, and it is similar to the sensations experienced by humans. The therapeutic effects of analgesics in animals are analogous to those in humans. For a long time, tribal people have relied on the aqueous juice of B. roxburghii’s pericarpium to relieve pain. Mice were utilised as test animals, and test medications were given to them orally. The hot plate, tail flick, and acetic acid induced writhing procedures were used to investigate analgesic effectiveness. In all of the tests, the butanolic fraction showed promising results. At a dose of 100 mg/kg, the butanolic fraction had a greater analgesic effect than the same fraction at a dose of 50 mg/kg. The dichloromethane fraction and aqueous residual have little analgesic efficacy. The findings show that the pericarpium of B. roxburghii may have analgesic properties.

Author(S) Details

Thirupathi Kaluvala
University College of Pharmaceutical Sciences, Satavahana University, Karimnagar, Telanagana, India.

Kranthi Raju Palle
University College of Pharmaceutical Sciences, Satavahana University, Karimnagar, Telanagana, India.

Shravan Kumar Dholi
Vaageswari Institute of Pharmaceutical Sciences, Karimnagar, Telanagana, India.

Sridhar Vanga
Vaageswari Institute of Pharmaceutical Sciences, Karimnagar, Telanagana, India.

View Book:- https://stm.bookpi.org/CAPRD-V3/article/view/4438

Leave A Comment

Categories