In organic synthesis, multicomponent reactions (MCR) and cascade reactions are frequently used. Different substituted pyrazoles are accessed using these two synthetic methods. In the first section, we're interested in learning how to make aminocyanopyrazoles using a multicomponent process. The current
Read MoreThis article has have as objective one: Present of two new algorithm for its application in the computers, with they we will can know all and of each of values 2𝑛 in polynomial time not only the individual values of
Read MoreThe hunt for plant-based remedies for atopic dermatitis (AD), a recurrent dermatological disorder with a high prevalence in tropical areas, has always piqued interest. Oroxylum indicum Linn (Bignoniaceae) is a commonly used medicinal plant that has not yet been scientifically
Read MoreA Quinolino novel series[3,2-f] [1,2,4] The [3,4-b] Triazolo [1,3,4] The Thiadiazepine (7a-i) derivatives incorporated with 3-(5--i) (benzofuran-2-yl) -1-phenyl-1H-3-yl pyrazol) Moiety was synthesised by a 5-(5-(benzofuran-2-yl)-1-phenyl-1H-pyrazol-3-yl)) one-point cyclo-condensation reaction. -4-amino-4H-1,2,4-triazole-3-thiol (4) in the presence of K2CO3 in DMF with 2-chloro-quinoline-3-carbaldehyde derivatives
Read MoreVarious biological activities have been found to demonstrate the compounds bearing sulfamoyl and acetamoyl groups. A series of O- and N-substituted derivatives, beginning with planetol (1), were synthesised in the present research work. Aq was used to treat the first
Read MoreDiscovery of the biological potentialities of cytoxazone by Kakeya’s research group has leveraged the development of studies aimed at the synthesis of this compound. The stereoselective total synthesis of (+)-epi-cytoxazone was performed satisfactorily in 8 steps, in 17% overall yield,
Read MoreAs a continuation of our research on developing anticancer agents and based on the proven proprieties of thieno[2,3‐b]pyridines as anticancer, we have designed to synthesize novel thieno[2,3‐ b]pyridine derivatives that incorporate different biologically active heterocycles through various chemical reactions. All
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