Synthesis and Characterization of Some Biologically Active Fluorinated Heterocycles Like Benzothiazepines & Pyrazolines
Fluorinated heterocycles like benzothiazepines & Pyrazolines shows apparent biological activities. 4-Bromo-2-fluorobenzaldehyde 1 when considered with substituted hydroxy acetophenones 2 yields chalcones 3. These chalcones were refluxed accompanying 2-aminothiophenol gave “2-[2-(4-bromo-2-fluorophenyl)-2,3-dihydro-1,5-benzothiazepin-4-yl]phenol” 4 and when treated accompanying hydrazine hydrate gave the compound
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