This study examined the kidney's response to therapeutic doses of acetaminophen (APAP) and light-to-moderate alcohol use while controlling for conditions including hypertension, diabetes, and obesity that might increase the kidney's susceptibility to APAP and/or alcohol toxicity. The study was a
Read MoreHypoestes rosea leaves are used as traditional medicine in most of Nigeria's Niger Delta regions and the western portion of Cameroon to treat a variety of diseases and sick states in children, such as fever, anaemia, and malaria. Despite its
Read MoreAcetaminophen (APAP) (N-acetyl-p-aminophenol) is a chemical compound utilised in paracetamol treatments to reduce pain and lower fever. In June 2009, an FDA advisory group issued a warning concerning the potential of APAP overdose due to the drug's side effects, which
Read MoreIntroduction: Drug overdose is the largest cause of liver injury in the world today, according to numerous reports. Natural antioxidant-rich diets have been shown to provide significant relief from drug-induced organ damage. The goal of this investigation was to see
Read MoreThe goal of this investigation was to see if Vernonia amygdalina aqueous extract could protect abino wistar rats against acetaminophen-induced liver injury.Methods: Twenty-five (25) albino rats weighing 120–20 g were allocated into five (5) groups, each with five (5) rats.
Read MoreThe effectiveness of glomerular filtration is measured by serum urea (sU), which is generated in the liver, and serum creatinine (sCr), which is a breakdown product of muscle cells. Both sU and sCr have low predictive accuracy for renal injury,
Read MoreApplication of orthodontic force causes an inflammatory event resulting in bone resorption and subsequent orthodontic tooth movement (OTM) in the periodontium. The release of inflammatory mediators such as E2 prostaglandins and Interleukin-1β serve as potent bone resorption stimulators. Strong force
Read More