Synthesis, Characterization and Biocompatibility of Maltodextrin-coated Cadmium Sulfide Quantum Dots in Experimental Models

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Semiconductor Quantum dots (QDs) have win quite a bit of celebrity due to their characteristics and extensive application in organic and biomedical research. However, these very same features present further troubles in comprehending, envisioning, and controlling possible antagonistic health results

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Determination of Cisplatin Effect on Head and Neck Squamous Cell Carcinoma Modulated by Erk1/2 Protein Kinases

The aim of this study was to investigate the role of extracellular signal-regulated kinases (ERK1/2) and/or p53 activation in the apoptotic process induced by cisplatin-CisPT treatment on two head and neck squamous cell carcinoma cell lines (FaDu and PE/CA-PJ49) and

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Methyl Donors Inhibit Panc-1 Cell Proliferation by Decreasing NFkB and Erk Signaling Levels and Raising E-Cadherin Expression

The physiology of cancer patients, particularly those with pancreatic cancer, may be improved by dietary methyl donors, which may also be utilised as intervention treatment. In this study, an aggressive pancreatic adenocarcinoma cell line (Panc-1) was treated with methyl-donors (L-methionine,

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Post-Translational Modification of SUMOylation and Cancer: A Brief Review

SUMOylation is a reversible post-translational modification that plays a role in DNA damage repair, immunological responses, carcinogenesis, cell cycle progression, and apoptosis. SUMO1, SUMO2/3, and SUMO4 are the four SUMO isoforms that have been identified. In complicated protein regulatory networks,

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Assessing the Correlation between Survivin and Bcl-2 Expression to Pathological Malignancy and Anti-apoptotic Property in Glial Cell Tumors

Apoptosis is controlled by a variety of variables whose mechanisms are unknown. Bcl-2 is a well-known apoptosis mediator. Survivin is also a new noble family inhibitor of apoptosis protein (IAP) that controls apoptosis in a different way than the Bcl-2

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Lectin-positive Spherical Deposits (SPD) in Molecular Layer of Hippocampal Dentate Gyrus of Dementia, Down’s Syndrome, and Schizophrenia: Mini Review

Lectins are proteins that bind (or crosslink) carbohydrates in a specific way. Recent research has revealed the role of glycosylation in disease aetiology. In dementia, Down's syndrome, and schizophrenia, we found lectin-positive spherical deposits (SPD) in the molecular layer of

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Assessing the Effects of Thermal Stimulation on Skeletal Muscle-Derived Cell Density

We looked into whether thermal stimulation could help prevent atherosclerotic cardiovascular disease in the past (ASCVD). Variations in the expression of associated genes were validated in studies utilising human skeletal muscle-derived cells (SMDC). A small decrease in the number of

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Determination of Electromagnetic Radiations and Liver Fibrosis Influences the “Lifespan” of Bone Marrow Cells

Exogenous and endogenous stimuli influence the speed and direction of cell formation in bone marrow. It was previously demonstrated that liver fibrosis affects the morphotypes of bone marrow cells. The response of bone marrow cells to liver fibrosis and electromagnetic

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