The Role of JNK, ERK and p38 Mitogen Activated Protein Kinases in the Response of Jurkat T Cells as a Model for T Cell Activatio

T lymphocyte activation necessitates at least two unique signals for a complete cellular response. The first signal involves antigen-specific peptide-MHC complexes binding to the T cell receptor (TCR). The interaction of costimulatory molecules on antigen presenting cells (APC) with the

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