Development of Cyclic Tetrapeptide as an EGFR Tyrosine Kinase Inhibitor Assayed by ELISA Experiment and Docking Study: A Novel Approach

The first objective of this project is to synthesize innovative cyclic peptides and test them as Epidermal Growth Factor Tyrosine Kinase Inhibitor (EGFR-TKI) by Enzyme-Linked Immuno Sorbent Assay (ELISA) experiment. The Cyclic Phe-Phe-Phe-Gly Tetrapeptide (CPTP) exhibited a strong IC50 of

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