Histone Deacetylase Inhibitors: An Innovative Revolution as Epigenetic Modifiers

The target-based epigenetic mechanisms, as well as the existing and potential therapeutic relevance of HDACIs in many malignant and non-malignant disorders, are discussed in this review article. Acetylation and deacetylation of histone proteins are important epigenetic changes that affect gene

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Current knowledge of Epigenetic Events in Multiple Myeloma

Multiple myeloma (MM) is a physiologically heterogeneous illness characterised by a wide range of chromosomal, genetic, and epigenetic alterations. Without affecting the DNA sequence, epigenetic changes can influence gene function. DNA methylation and post-translational alteration of histone proteins (histone methylation,

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