Phosphatidylinositol 3′ Kinase (PI3K), A Crucial Regulator of Epidermal Growth Factor Receptor (EGFR) Modulated MMP-2, MMP-9 and MT1-MMP Expression in Breast Cancer Cells

In breast cancer, tumour metastasis is responsible for the majority of mortality. Breast cancers with elevated epidermal growth factor receptor (EGFR) activity have been identified with increased tumour invasion and poorer prognosis. Increased expression of MMP-2, MMP-9 and MT1-MMP matrix

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