Study on Pd(PPh3)4 Catalyzed Synthesis of Indazole Derivatives as Potent Anticancer Drug

By coupling with several arylboronic acids and methylation using two different methods, a sequence of 3-aryl indazoles and 1-methyl-3-aryl indazole derivatives are prepared with exceptional yields. The anticancer activity of the indazole derivatives (3a-3j) and their N-methyl derivatives (5a-5j) is

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